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KMID : 0364219650080020033
Korean Journal of Zoology
1965 Volume.8 No. 2 p.33 ~ p.36
The Modification of X-ray induced Mutation in Paramecium by Pre-and Post-irradiation Treatment with Colchicine
Kang Yung-Sun

Kang Hyun-Sam
Abstract
We have carried out a study on the modification of the frequency of X-ray induced lethal and slow growing mutations by colchincine treatment before and after X-ray irradiation in Paramecium aurelia. 1. Lethal and slow-growing mutation induced by X-ray in Paramecium aurelia were reduced by colchicine treatment. 2. The effects of colchicine on the X-ray induced mutations were remarkable in the radiosensitive stages of cell division. 3. The pre-irradiation treatment with colchicine showed no significant influence on the frequency of mutations. 4. It is believed that the reduction of mutation induced by X-ray after treatment with colchicine was due to the fact that the delay of the cell division allowed more time for the pre-mutational damage to recover.
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